Genetics of Complex Phenotypes

Head of Research Unit
Anna Alisi


The Research Unit studies the pathophysiological mechanisms of non-alcoholic fatty liver disease (NAFLD) and other childhood liver diseases with multifactorial etiology, in order to identify new therapeutic targets with the aim of achieving results that allow the development of clinical decision support systems. 

The Unit is committed to identifying and validating genetic, epigenetic and circulating diagnostic markers of clinical impact and to studying new therapeutic strategies for NAFLD, in order to improve the clinical picture and liver parameters of those suffering from this pathology.

It also investigates the genetic, epigenetic and inflammatory mechanisms that lead to some chronic non-communicable liver diseases and their associated comorbidities. 

The Unit is made up of a multidisciplinary group made up of cellular and molecular biologists, biochemists and clinicians who collaborate by making their skills available in a spirit of sharing and with the common intention of offering the best answer to scientific and technological questions that arise along the way.

“The dream of Bambino Gesù Hospital,
the dream of the Pope, is to help bring
science and humanity to all children with
very severe diseases who need to be treated”
Pope Francis